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Before initiating actonel treatment for the treatment and prevention of glucocorticoid-induced osteoporosis, the sex steroid hormonal status of both men and women should be ascertained and appropriate replacement considered.

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similar to other bisphosphonates, treatment during mating and gestation with doses of actonel sodium approximately the same as the 30 mg day human dose resulted in periparturient hypocalcemia and mortality in pregnant rats allowed to deliver.

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and last week, the two companies that jointly sell the osteoporosis drug actonel agreed to reimburse the insurer health alliance for the costs of treating fractures suffered by patients taking that medicine.

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